Lab Members

PostDocs



Dr. Conradin Baumgartl (11/21-)

- Epigenetics of AAV episome using nanpore and CUT&Tag sequencing

- Interrogating nucleotide patterns in the AAV genome sequence




Dr. Jan Bieri (03/25-)

- Engineering of AAV capsids through rational design

- Hybrid virus design using AAV and B19V



Dr. Felix Bubeck (04/20-)

- Deciphering the impact of engineered ITR sequences on AAV vector production & function

- Alternative cargo modalities in AAV vectors



Dr. Deepak K. Gupta (03/23-)

- Analysis of AAV NGS Data

- Development of methods and bioinformatics pipelines for NGS Data analysis




Dr. Emre U. Kul (06/25-)

- Rational engineering and retargeting of AAV vectors for CNS gene therapy approaches

- Humanized experimental models to evaluate AAV tropism and translational relevance




Dr. Kristian Leite (03/22-)

- In vivo AAV library screens in major organs





Dr. Ning Meng (05/19-)

- Genetic code expansion using AAV vectors

- AAV vector retargeting through combinatorial peptide display



Dr. Olena Maiakovska (11/20-)

- Analysis of AAV next-generation sequencing data (Illumina, PacBio)

- Establishment of user-friendly AAV alignment and analysis tools




Dr. Kleopatra Rapti (XX/XX-)

- Directed evolution of AAV vectors in the liver, eye and kidney

- Experimental & bioinformatic high-throughput screening pipelines




Dr. Sergio D. M. Velasquez (07/22-)

- Development of novel gene therapy vectors derived from Bocarvirus

- Engineering of synthetic circuits to control bocavirus vector production




Dr. Man Xu (09/23-)

- Directed evolution of AAV vectors in the liver, eye and kidney

- Experimental & bioinformatic high-throughput screening pipelines


PhD students



Nico Fischer (10/20-)

- Combinatorial CRISPR/RNAi strategies against HBV/HDV





Heinz-Georg "Quique" Hildebrand (05/21-)

- AAV engineering for expression of broady neutralizing antibodies





Jixin Liu (01/22-)

- AAV Rep protein engineering

- AAV screening in the CNS and musculature



Sharon Portelli (06/25-)

- Elucidating the intracellular dynamics of Bocarvirus capsids as viral vectors



Yumi Sano (07/23-)

- Capsid engineering of bocavirus to improve transduction & identifying physicochemical properties of bocavirus



Technicians



Emma Gerstmann (10/20-)





Chiara Krämer (03/16-)





Ellen Wiedtke (02/08-)

- all aspects of AAV production for internal and external use


Students

  • Miguel Palma-Marques (2025)
  • Christopher Hub (2025)
  • Ante Mrkonjic (2025)
  • Doris Zimmermann (2026)
  • Jordan Dattero (2025)
  • David Triebel (2025)
  • Timur Bozkurt (2026)
  • Linda Ruck (2025)
  • Sophia Krastev (2025)
  • Katya Georgieva (2025
  • Julia Oesterle (2026)