Postdocs
Dr. Kleopatra Rapti
- Directed evolution of AAV vectors in the liver, eye and kidney
- Experimental & bioinfomatic high-throughput screening pipelines
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Dr. Margarita Zayas (07/16-)
- Directed evolution of AAV capsids for muscle and CNS gene therapy
- Combinatorial AAV capsid evolution via DNA shuffling & peptide display
Dr. Ali Ghanem (05/19-)
- Evolution of cell type-specific AAV capsids in the liver
- Tracking of barcoded AAV capsid variants on the single-cell level
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Dr. Joanna Szumska (07/20-)
- Molecular evolution of synthetic AAV capsids in the CNS of primates
- Combinatorial AAV evolution via DNA shuffling and peptide display
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Dr. Olena Maiakovska (11/20-)
- Analysis of AAV next-generation sequencing data (Illumina, PacBio)
- Establishment of user-friendly AAV alignment and analysis tools
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Dr. Teng Wei Koay (03/22-)
- In vivo AAV library screens in major organs
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PhD students
Ning Meng (05/19-)
- Genetic code expansion using AAV vectors
- AAV vector retargeting through combinatorial peptide display
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Felix Bubeck (04/20-)
- Synthetic AAV ITRs for enhanced vector persistence
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Jonas Becker (03/20-)
- Novel in vivo AAV capsid evolution technologies
- AAV-based CRISPR/Cas applications including SARS_CoV-2
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Nico Fischer (10/20-)
- Combinatorial CRISPR/RNAi strategies against HBV/HDV
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Heinz-Georg (Quique) Hildebrand (05/21-)
- AAV engineering for expression of broadly neutralizing antibodies
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