People Postdocs Dr. Kleopatra Rapti- Directed evolution of AAV vectors in the liver, eye and kidney - Experimental & bioinfomatic high-throughput screening pipelines Dr. Jihad El Andari (07/16-)- Directed evolution of AAV capsids for muscle and CNS gene therapy - Combinatorial AAV capsid evolution via DNA shuffling & peptide display Dr. Mareike Hoffmann (01/20-)- Molecular evolution of novel AAV variants in the muscle and CNS - Engineering of light- and miRNA-regulated AAV vectors Dr. Ali Ghanem (05/19-)- Evolution of cell type-specific AAV capsids in the liver - Tracking of barcoded AAV capsid variants on the single-cell level Dr. Mischa Schwendy (05/19-)Postdoc working on in vivo regulation of AAV vector gene expression Dr. Joanna Szumska (07/20-)- Molecular evolution of synthetic AAV capsids in the CNS of monkeys - Combinatorial AAV evolution via DNA shuffling and peptide display Dr. Olena Maiakovska (11/20-)- Analysis of AAV next-generation sequencing data (Illumina, PacBio) - Establishment of user-friendly AAV alignment and analysis tools PhD students Ning Meng (05/19-)- Genetic code expansion using AAV vectors - AAV vector retargeting through combinatorial peptide display Jonas Becker (03/20-)- Novel in vivo AAV capsid evolution technologies - CRISPR/Cas applications Felix Bubeck (04/20-)- Synthetic AAV ITRs for enhances vector persistence Nico Fischer (10/20-)- Combinatorial CRISPR/RNAi strategies against HBV/HDV Technicians Ellen Wiedtke (02/08-)PhD student working on genetic code expansion and parvoviral retargeting Chiara Krämer (03/16-)PhD student working on genetic code expansion and parvoviral retargeting Cinja Sackmann (01/17-)PhD student working on genetic code expansion and parvoviral retargeting Lena Naber (09/20-)Technician in training ("Azubi") Emma Gerstmann (10/20-)Technician