People

Postdocs

Dr. Kleopatra Rapti

- Directed evolution of AAV vectors in the liver, eye and kidney
- Experimental & bioinfomatic high-throughput screening pipelines

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Dr. Olena Maiakovska (11/20-)

- Analysis of AAV next-generation sequencing data (Illumina, PacBio)
- Establishment of user-friendly AAV alignment and analysis tools

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Dr. Teng Wei Koay (03/22-)

- In vivo AAV library screens in major organs
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Dr. Kristian Leite (03/22-)

- In vivo AAV library screens in major organs
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Dr. Deepak K. Gupta (03/23-)

- Analysis of AAV NGS data
- Development of methods and bioinformatics pipelines for NGS data analysis

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Dr. Sergio D. M. Velasquez (07/22-)

- Development of novel gene therapy vectors derived from Bocavirus
- Engineering of synthetic circuits to control bocavirus vector production

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Dr. Man Xu (09/23-)

- Engineering of synthetic AAV capsids through peptide display & shuffling
- Directed evolution of AAV capsids in multiple major organs in animal models

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Dr. Esra Oktay (11/23-)

- Design and synthesis of hybrid AAV - origami (Virogami) nanoparticles
- Targeted in vivo gene delivery using Virogami particles

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Dr. Poonam Vishwakarma (12/23-)

- Design and synthesis of hybrid AAV - origami (Virogami) nanoparticles
- Targeted in vivo gene delivery using Virogami particles

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PhD students

Ning Meng (05/19-)

- Genetic code expansion using AAV vectors
- AAV vector retargeting through combinatorial peptide display

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Felix Bubeck (04/20-)

- Synthetic AAV ITRs for enhanced vector persistence

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Jonas Becker (03/20-)

- Novel in vivo AAV capsid evolution technologies
- AAV-based CRISPR/Cas applications including SARS_CoV-2

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Nico Fischer (10/20-)

- Combinatorial CRISPR/RNAi strategies against HBV/HDV

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Heinz-Georg (Quique) Hildebrand (05/21-)

- AAV engineering for expression of broadly neutralizing antibodies

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Conradin Baumgartl (11/21-)

- Epigenetic studies on the AAV episome

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Jixin Liu (01/22-)

- AAV Rep protein engineering
- AAV screening in the CNS and musculature

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Yumi Sano (01/22-)

- AAV Rep protein engineering
- AAV screening in the CNS and musculature

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Technicians

Ellen Wiedtke (02/08-)

- All aspects of AAV production for internal and external use

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Chiara Krämer (03/16-)

- Preparation of samples for NGS analyses and various other expertises

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Lena Naber (09/20-)

Technician

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Emma Gerstmann (10/20-)

Technician

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