People

Postdocs

Dr. Kleopatra Rapti

- Directed evolution of AAV vectors in the liver, eye and kidney
- Experimental & bioinfomatic high-throughput screening pipelines

Dr. Jihad El Andari (07/16-)

- Directed evolution of AAV capsids for muscle and CNS gene therapy
- Combinatorial AAV capsid evolution via DNA shuffling & peptide display

Dr. Mareike Hoffmann (01/20-)

- Molecular evolution of novel AAV variants in the muscle and CNS
- Engineering of light- and miRNA-regulated AAV vectors

Dr. Ali Ghanem (05/19-)

- Evolution of cell type-specific AAV capsids in the liver
- Tracking of barcoded AAV capsid variants on the single-cell level

Dr. Mischa Schwendy (05/19-)

Postdoc working on in vivo regulation of AAV vector gene expression

Dr. Joanna Szumska (07/20-)

- Molecular evolution of synthetic AAV capsids in the CNS of monkeys
- Combinatorial AAV evolution via DNA shuffling and peptide display

Dr. Olena Maiakovska (11/20-)

- Analysis of AAV next-generation sequencing data (Illumina, PacBio)
- Establishment of user-friendly AAV alignment and analysis tools

PhD students

Ning Meng (05/19-)

- Genetic code expansion using AAV vectors
- AAV vector retargeting through combinatorial peptide display

Jonas Becker (03/20-)

- Novel in vivo AAV capsid evolution technologies
- CRISPR/Cas applications

Felix Bubeck (04/20-)

- Synthetic AAV ITRs for enhances vector persistence

Nico Fischer (10/20-)

- Combinatorial CRISPR/RNAi strategies against HBV/HDV

Technicians

Ellen Wiedtke (02/08-)

PhD student working on genetic code expansion and parvoviral retargeting

Chiara Krämer (03/16-)

PhD student working on genetic code expansion and parvoviral retargeting

Cinja Sackmann (01/17-)

PhD student working on genetic code expansion and parvoviral retargeting

Lena Naber (09/20-)

Technician in training ("Azubi")

Emma Gerstmann (10/20-)

Technician